SMARCC2 and RAB1B

Data Source:
BioGRID (two hybrid)

		SMARCC2	RAB1B
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	RAB1B, member RAS oncogene family
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GO Annotations	Cellular Component	Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Virion Assembly Post-translational Protein Modification COPII Vesicle Coating Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Asthma ( 31619474) Refractive error ( 32231278)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		26 interacting genes: ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 KRT27 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SMARCB1 SP1 SRGAP3 TAF15 TERF1 TERF2IP	11 interacting genes: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RABIF RUSC2 SMARCC2 TOMM40L
Entrez ID		6601	81876
HPRD ID		03437	11469
Ensembl ID		ENSG00000139613	ENSG00000174903
Uniprot IDs		A0A024RB22 F8VXC8 Q8TAQ2	Q9H0U4
PDB IDs		6KAG 6LTH 6LTJ	3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK 6SKU
Enriched GO Terms of Interacting Partners?
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