SMARCC2 and BAZ1B

Data Source:
HPRD (in vivo, in vitro)

		SMARCC2	BAZ1B
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	bromodomain adjacent to zinc finger domain 1B
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GO Annotations	Cellular Component	Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Condensed Chromosome Nucleoplasm Pericentric Heterochromatin Nuclear Body Nuclear Replication Fork
	Molecular Function	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Histone Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Gene Expression, Epigenetic
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS		Asthma ( 31619474) Refractive error ( 32231278)	C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Lamb consumption ( 32066663) Malaria ( 31844061) Meat-related diet ( 32066663) Metabolic syndrome ( 31589552) Migraine ( 27182965) Non-oily fish consumption ( 32066663) Platelet count ( 32888494) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549) Triglycerides ( 20864672) Urate levels ( 31985003 23263486) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		26 interacting genes: ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 KRT27 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SMARCB1 SP1 SRGAP3 TAF15 TERF1 TERF2IP	10 interacting genes: CDT1 MTNR1A MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2
Entrez ID		6601	9031
HPRD ID		03437	10416
Ensembl ID		ENSG00000139613	ENSG00000009954
Uniprot IDs		A0A024RB22 F8VXC8 Q8TAQ2	Q9UIG0
PDB IDs		6KAG 6LTH 6LTJ	1F62 5NNF
Enriched GO Terms of Interacting Partners?
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