SGCG and DNAJB6

Data Source:
BioGRID (two hybrid, imaging technique)

		SGCG	DNAJB6
Description		sarcoglycan gamma	DnaJ heat shock protein family (Hsp40) member B6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Sarcoglycan Complex Integral Component Of Membrane Sarcolemma	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Muscle Organ Development Cardiac Muscle Tissue Development Heart Contraction	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS		Alanine aminotransferase levels ( 31219225) Asthma ( 27611488) Atrial fibrillation ( 30061737) Bipolar disorder ( 21738484) Central corneal thickness ( 29760442) Corneal structure ( 23291589) Number of alcoholic drinks required to feel an effect (first five times drinking) ( 31270906) Type 2 diabetes ( 23300278)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		20 interacting genes: APP CCT6A CLDN5 DNAJB6 DYSF ENO1 ENO3 FLNC HSPA1B MYBPC1 MYBPC2 MYLPF PSAP PYGM SGCB SGCD SPACA1 SSPN SUCLG2 TTN	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		6445	10049
HPRD ID		07039	07107
Ensembl ID		ENSG00000102683	ENSG00000105993
Uniprot IDs		Q13326	A0A0J9YX62 O75190
PDB IDs			6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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