SGCG and SUCLG2

Data Source:
BioGRID (two hybrid)

		SGCG	SUCLG2
Description		sarcoglycan gamma	succinate-CoA ligase GDP-forming subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Sarcoglycan Complex Integral Component Of Membrane Sarcolemma	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex Succinate-CoA Ligase Complex (GDP-forming)
	Molecular Function	Protein Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding GTP Binding GDP Binding Protein-containing Complex Binding
	Biological Process	Muscle Organ Development Cardiac Muscle Tissue Development Heart Contraction	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process
Pathways			Citric acid cycle (TCA cycle)
Drugs			Phenethyl Isothiocyanate
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS		Alanine aminotransferase levels ( 31219225) Asthma ( 27611488) Atrial fibrillation ( 30061737) Bipolar disorder ( 21738484) Central corneal thickness ( 29760442) Corneal structure ( 23291589) Number of alcoholic drinks required to feel an effect (first five times drinking) ( 31270906) Type 2 diabetes ( 23300278)	Blood metabolite levels ( 24816252) Body mass index ( 28552196) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 25027320) Corneal astigmatism ( 22144915) Diabetic kidney disease ( 26305897) FEV1 ( 30804560) Height ( 20881960) Hip circumference ( 28552196) IgE levels ( 23146381) Lung function (FVC) ( 28166213 30804560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		20 interacting genes: APP CCT6A CLDN5 DNAJB6 DYSF ENO1 ENO3 FLNC HSPA1B MYBPC1 MYBPC2 MYLPF PSAP PYGM SGCB SGCD SPACA1 SSPN SUCLG2 TTN	3 interacting genes: GPR143 SGCG SUCLG1
Entrez ID		6445	8801
HPRD ID		07039	06799
Ensembl ID		ENSG00000102683	ENSG00000172340
Uniprot IDs		Q13326	Q96I99
PDB IDs			6WCV
Enriched GO Terms of Interacting Partners?
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