SRSF3 and NXF1

Data Source:
HPRD (in vitro)

		SRSF3	NXF1
Description		serine and arginine rich splicing factor 3	nuclear RNA export factor 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Speck	Transcription Export Complex Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Nuclear Inclusion Body
	Molecular Function	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	RNA Export From Nucleus MRNA Export From Nucleus Viral Process Poly(A)+ MRNA Export From Nucleus
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		39 interacting genes: APP CHD1 CIRBP CLK1 CLK2 CLK3 CNNM3 DUX4 EXOSC6 GEMIN2 HNRNPK IL7R LNX1 NXF1 PCBP1 PCBP2 PCBP3 PCDHB14 PRPF31 RBM3 RBM7 RBMX RBMY1A1 RNPS1 RPL9 SCAF11 SDCBP SREK1 SRPK1 SRPK2 SRSF2 SRSF8 TRA2B U2AF1 U2AF1L5 U2AF2 YWHAB YWHAG YWHAQ	108 interacting genes: ALYREF AUNIP BACH2 BECN1 BIN3 BIRC2 BLMH BTBD18 C10orf55 C12orf40 CAMK2G CCDC120 CCDC196 CCDC197 CCDC7 CDYL2 CLK2 CLK3 CSNK2A1 DHX9 DVL3 ECSIT EIF4A3 ELAVL4 ESRRA FAM9A FTO GFAP GOLGA6L9 GPBP1 GTPBP2 HNRNPUL1 HOMEZ HOXA1 HSF2BP IMPA1 IPO11 IPO4 ISY1-RAB43 KATNBL1 KCTD5 KCTD7 KRT40 LCE3E LDOC1 LUZP4 MAGOH MAP1A MAP1B MBD3L1 MID2 MRNIP MTUS2 NKAPD1 NME4 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 PIH1D2 PPP1R12C PRKAR1B PRPH PRR3 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A RPRD1A SGTA SH2D3A SH3GLB2 SLAIN1 SNW1 SPATC1L SRPK2 SRSF1 SRSF3 SRSF7 STRAP SYCP3 TBC1D14 TCP10L TEX9 THOC5 TIFA TNFAIP1 TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN1 UBQLN4 UPF3A VPS28 XIST ZBED2 ZNF250 ZNF343 ZNF438
Entrez ID		6428	10482
HPRD ID		04530	04035
Ensembl ID		ENSG00000112081	ENSG00000162231
Uniprot IDs		B2R6F3 P84103	Q59E96 Q9UBU9
PDB IDs		2I2Y 2I38	1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U
Enriched GO Terms of Interacting Partners?
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