NXF1 and PPP1R12C

Data Source:
BioGRID (two hybrid)

		NXF1	PPP1R12C
Description		nuclear RNA export factor 1	protein phosphatase 1 regulatory subunit 12C
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Nuclear Inclusion Body	Cytoplasm Cytoskeleton
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Enzyme Inhibitor Activity Protein Binding Phosphatase Regulator Activity Protein Kinase Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Viral Process Poly(A)+ MRNA Export From Nucleus	Signal Transduction Negative Regulation Of Catalytic Activity
Pathways		Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		108 interacting genes: ALYREF AUNIP BACH2 BECN1 BIN3 BIRC2 BLMH BTBD18 C10orf55 C12orf40 CAMK2G CCDC120 CCDC196 CCDC197 CCDC7 CDYL2 CLK2 CLK3 CSNK2A1 DHX9 DVL3 ECSIT EIF4A3 ELAVL4 ESRRA FAM9A FTO GFAP GOLGA6L9 GPBP1 GTPBP2 HNRNPUL1 HOMEZ HOXA1 HSF2BP IMPA1 IPO11 IPO4 ISY1-RAB43 KATNBL1 KCTD5 KCTD7 KRT40 LCE3E LDOC1 LUZP4 MAGOH MAP1A MAP1B MBD3L1 MID2 MRNIP MTUS2 NKAPD1 NME4 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 PIH1D2 PPP1R12C PRKAR1B PRPH PRR3 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A RPRD1A SGTA SH2D3A SH3GLB2 SLAIN1 SNW1 SPATC1L SRPK2 SRSF1 SRSF3 SRSF7 STRAP SYCP3 TBC1D14 TCP10L TEX9 THOC5 TIFA TNFAIP1 TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN1 UBQLN4 UPF3A VPS28 XIST ZBED2 ZNF250 ZNF343 ZNF438	23 interacting genes: ATP6V1H ATXN7 BHLHA9 C1orf109 CACNA1A CCDC185 CDC42BPA EHHADH EXOC3 IL16 IMP3 MPRIP MYL2 NOD2 NXF1 PAFAH1B2 PPP1CB RBM17 SMAD3 SPECC1L THOC1 TSFM USHBP1
Entrez ID		10482	54776
HPRD ID		04035	11452
Ensembl ID		ENSG00000162231	ENSG00000125503
Uniprot IDs		Q59E96 Q9UBU9	Q9BZL4
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U
Enriched GO Terms of Interacting Partners?
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