NXF1 and TRA2B

Data Source:
BioGRID (two hybrid)

		NXF1	TRA2B
Description		nuclear RNA export factor 1	transformer 2 beta homolog
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GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Nuclear Inclusion Body	Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Viral Process Poly(A)+ MRNA Export From Nucleus	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Glucose Stimulus Embryonic Brain Development
Pathways		Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		108 interacting genes: ALYREF AUNIP BACH2 BECN1 BIN3 BIRC2 BLMH BTBD18 C10orf55 C12orf40 CAMK2G CCDC120 CCDC196 CCDC197 CCDC7 CDYL2 CLK2 CLK3 CSNK2A1 DHX9 DVL3 ECSIT EIF4A3 ELAVL4 ESRRA FAM9A FTO GFAP GOLGA6L9 GPBP1 GTPBP2 HNRNPUL1 HOMEZ HOXA1 HSF2BP IMPA1 IPO11 IPO4 ISY1-RAB43 KATNBL1 KCTD5 KCTD7 KRT40 LCE3E LDOC1 LUZP4 MAGOH MAP1A MAP1B MBD3L1 MID2 MRNIP MTUS2 NKAPD1 NME4 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 PIH1D2 PPP1R12C PRKAR1B PRPH PRR3 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A RPRD1A SGTA SH2D3A SH3GLB2 SLAIN1 SNW1 SPATC1L SRPK2 SRSF1 SRSF3 SRSF7 STRAP SYCP3 TBC1D14 TCP10L TEX9 THOC5 TIFA TNFAIP1 TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN1 UBQLN4 UPF3A VPS28 XIST ZBED2 ZNF250 ZNF343 ZNF438	110 interacting genes: CDK6 CLK1 CLK3 EPM2AIP1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM MAGOHB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NGFR NXF1 PCDHB14 RBMX RBMXL2 RBMY1A1 RBMY1F RBMY1J RNPS1 SREK1 SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF8 SRSF9 TNPO3 U2AF1 U2AF1L5 YTHDC1 YWHAG YWHAZ ZRANB2
Entrez ID		10482	6434
HPRD ID		04035	04097
Ensembl ID		ENSG00000162231	ENSG00000136527
Uniprot IDs		Q59E96 Q9UBU9	P62995
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U	2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?
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