SELPLG and ECSIT

Data Source:
BioGRID (affinity chromatography technology)

		SELPLG	ECSIT
Description		selectin P ligand	ECSIT signaling integrator
Image			No pdb structure
GO Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Mitochondrial Respiratory Chain Complex I Assembly Innate Immune Response Regulation Of Oxidoreductase Activity Regulation Of Protein Complex Stability
Pathways		Cell surface interactions at the vascular wall	MyD88:MAL(TIRAP) cascade initiated on plasma membrane Complex I biogenesis TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)	Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		14 interacting genes: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN	52 interacting genes: A2M AP1M2 APOE APP BFSP2 BLMH C1orf109 CDC37 CEP55 CTNNA3 CYP2C18 CYP2C8 CYP2C9 DNAJB1 DTX2 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH GEM IFIT3 IFIT5 IMMT LONP1 LOXL4 MAGEB2 MAST1 MKRN3 NFKB1 NXF1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SETDB1 SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TARS3 TRAF6 TRIM59 TSSK3
Entrez ID		6404	51295
HPRD ID		02845	12225
Ensembl ID		ENSG00000110876	ENSG00000130159
Uniprot IDs		Q14242	Q9BQ95
PDB IDs		1G1S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?