GPSM3 and BMF

Data Source:
BioGRID (two hybrid)

		GPSM3	BMF
Description		G protein signaling modulator 3	Bcl2 modifying factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Acrosomal Vesicle Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex
	Molecular Function	Molecular_function Protein Binding GTPase Regulator Activity	Protein Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Autophagy Positive Regulation Of Protein-containing Complex Assembly Cellular Response To UV Positive Regulation Of Apoptotic Process Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		G alpha (i) signalling events	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria
Drugs
Diseases
GWAS		Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Chronic lymphocytic leukemia ( 28165464 26956414 24292274) Dehydroepiandrosterone sulphate levels ( 21533175) Endometrial cancer ( 30093612 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Ewing sarcoma ( 22327514) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581	26 interacting genes: AQP1 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BCL2L2-PABPN1 CTAG1A CTAG1B CXCL9 DYNLL1 DYNLL2 GPSM3 LCN2 MAPK8 MCL1 MGAT5B MYO5A NNMT RECK REL SEC14L4 SHC3 TCF12 TFIP11 TRIM54
Entrez ID		63940	90427
HPRD ID		13605	05881
Ensembl ID		ENSG00000213654	ENSG00000104081
Uniprot IDs		A0A024RCP6 Q9Y4H4	Q96LC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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