GPSM3 and RSPO4

Data Source:
BioGRID (two hybrid)

		GPSM3	RSPO4
Description		G protein signaling modulator 3	R-spondin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Extracellular Region
	Molecular Function	Molecular_function Protein Binding GTPase Regulator Activity	Protein Binding Heparin Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Nail Development
Pathways		G alpha (i) signalling events	Regulation of FZD by ubiquitination
Drugs
Diseases			Anonychia congenita
GWAS		Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)	Blood protein levels ( 30072576) Lean body mass ( 28552196) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321)
Interacting Genes		45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581	15 interacting genes: ANKRD11 DHX57 GNG13 GPSM3 GUCD1 HGS KLHL38 LGR4 MAPK9 MKRN3 PIH1D2 STK16 USP20 ZNF330 ZNF77
Entrez ID		63940	343637
HPRD ID		13605	18788
Ensembl ID		ENSG00000213654	ENSG00000101282
Uniprot IDs		A0A024RCP6 Q9Y4H4	Q2I0M5
PDB IDs
Enriched GO Terms of Interacting Partners?
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