RUNDC3A and RAP2B

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RUNDC3A	RAP2B
Description		RUN domain containing 3A	RAP2B, member of RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Cytosol Plasma Membrane Bicellular Tight Junction Membrane Specific Granule Membrane Cell-cell Contact Zone Membrane Raft Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding GTPase Regulator Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Catalytic Activity	Signal Transduction Microvillus Assembly Platelet Activation Negative Regulation Of Cell Migration Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Neutrophil Degranulation Regulation Of Protein Tyrosine Kinase Activity Platelet Aggregation Establishment Of Endothelial Intestinal Barrier
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Cerebral amyloid deposition (PET imaging) ( 30361487) Chronotype ( 30696823) Cutaneous melanoma or hair colour ( 32341527) Metabolite levels ( 23823483) PR interval ( 32439900) Serum sulfate level ( 27412988)
Interacting Genes		35 interacting genes: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E ENKD1 FAM161A GEM GFI1B HTR6 LNX1 MAGEB4 MAGOHB MBD3L2 MRPL15 MYO15B PRPF31 RAP1A RAP2A RAP2B SDCBP SYT17 TBRG1 TEAD4 TFPT TSGA10IP TSHR UBTFL1 USP2 ZNF250 ZNF417 ZNF587 ZNF821 ZNF835	9 interacting genes: CAMK2B PDE6D RALGDS RAP1GDS1 RAPGEF1 RAPGEF2 RAPGEF5 RASSF5 RUNDC3A
Entrez ID		10900	5912
HPRD ID		16106	01548
Ensembl ID		ENSG00000108309	ENSG00000181467
Uniprot IDs		Q59EK9	P61225
PDB IDs			1N4P 1N4Q 1N4R
Enriched GO Terms of Interacting Partners?
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