PEX5 and ZFAND3

Data Source:
BioGRID (two hybrid)

		PEX5	ZFAND3
Description		peroxisomal biogenesis factor 5	zinc finger AN1-type containing 3
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GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Golgi Apparatus Cytosol Membrane Protein-containing Complex
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein N-terminus Binding Protein Sequestering Activity	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Ubiquitination Negative Regulation Of Protein-containing Complex Assembly Protein Import Into Peroxisome Membrane
Pathways		Pexophagy
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917) Refractive error ( 32231278)	Acne (severe) ( 24927181) Insulin resistance/response ( 21901158) Post bronchodilator FEV1/FVC ratio ( 26634245) Type 2 diabetes ( 22158537)
Interacting Genes		76 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 GDPD5 GLMN GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HNRNPH1 HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 PSAP RPL14 S100A6 SCARB1 SCP2 SCRN2 SIRT3 SLC27A2 SNUPN SSTR5 TIMMDC1 TINF2 TM6SF1 TOMM7 USP2 USP9X ZFAND3 ZNF772	8 interacting genes: FAM25A FAM25C FAM25G GOLM1 INCA1 MAP3K1 PEX5 UBC
Entrez ID		5830	60685
HPRD ID		02684	12121
Ensembl ID		ENSG00000139197	ENSG00000156639
Uniprot IDs		A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542	A0A024RD12 E2QRF5 Q9H8U3
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO	1X4W
Enriched GO Terms of Interacting Partners?
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