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PURA and MIRLET7C
Data Source:
BioGRID
(unspecified method)
PURA
MIRLET7C
Description
purine rich element binding protein A
microRNA let-7c
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Dendrite Cytoplasm
Neuronal Cell Body
Postsynapse
Glutamatergic Synapse
Extracellular Space
Nucleus
Cytoplasm
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Translation Repressor Activity, MRNA Regulatory Element Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Double-stranded Telomeric DNA Binding
Single-stranded DNA Binding
RNA Binding
Protein Binding
Transcription Factor Binding
Purine-rich Negative Regulatory Element Binding
SMAD Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Translation
Cell Differentiation
Lymphocyte Proliferation
Epithelial Cell Proliferation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-8 Production
Gene Silencing By MiRNA
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
Pathways
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
57 interacting genes:
ADAP1
CCNT1
CDK5
E2F1
IL7R
MIR1-1
MIR106B
MIR122
MIR128-1
MIR128-2
MIR140
MIR143
MIR155
MIR15B
MIR16-2
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR205
MIR20B
MIR21
MIR221
MIR222
MIR25
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR7-1
MIR7-2
MIR9-2
MIR92A2
MIR93
MIRLET7A1
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PTEN
PURB
RAF1
RB1
SP1
YBX1
96 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
ATXN2L
C1QBP
CHERP
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PLOD1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM4B
RBMS2
RTCA
RTCB
SART3
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
5813
406885
HPRD ID
02721
Ensembl ID
ENSG00000185129
ENSG00000199030
Uniprot IDs
Q00577
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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