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PURA and CCNT1
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
PURA
CCNT1
Description
purine rich element binding protein A
cyclin T1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Dendrite Cytoplasm
Neuronal Cell Body
Postsynapse
Glutamatergic Synapse
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Cyclin/CDK Positive Transcription Elongation Factor Complex
P-TEFb Complex
Molecular Function
Translation Repressor Activity, MRNA Regulatory Element Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Double-stranded Telomeric DNA Binding
Single-stranded DNA Binding
RNA Binding
Protein Binding
Transcription Factor Binding
Purine-rich Negative Regulatory Element Binding
SMAD Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
Chromatin Binding
Protein Binding
Transcription Factor Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
RNA Polymerase Binding
7SK SnRNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Translation
Cell Differentiation
Lymphocyte Proliferation
Epithelial Cell Proliferation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cell Cycle
Viral Process
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Positive Regulation By Host Of Viral Transcription
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Cell Division
Negative Regulation Of MRNA Polyadenylation
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Interactions of Tat with host cellular proteins
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Clozapine-induced agranulocytosis (
25187353
)
Interacting Genes
57 interacting genes:
ADAP1
CCNT1
CDK5
E2F1
IL7R
MIR1-1
MIR106B
MIR122
MIR128-1
MIR128-2
MIR140
MIR143
MIR155
MIR15B
MIR16-2
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR205
MIR20B
MIR21
MIR221
MIR222
MIR25
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR7-1
MIR7-2
MIR9-2
MIR92A2
MIR93
MIRLET7A1
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PTEN
PURB
RAF1
RB1
SP1
YBX1
26 interacting genes:
AFF4
AHR
BRD4
CDK9
CEBPB
ESR1
GRIPAP1
GRN
GTF2F1
HEXIM1
HEXIM2
HIC2
HTATSF1
HTN1
KAT2B
MDFIC
MYC
NCOA2
NUFIP1
PML
POLR2A
PRKCI
PURA
RN7SK
SKP2
SUPT5H
Entrez ID
5813
904
HPRD ID
02721
03938
Ensembl ID
ENSG00000185129
ENSG00000129315
Uniprot IDs
Q00577
A8K4M5
O60563
PDB IDs
2PK2
3BLH
3BLQ
3BLR
3LQ5
3MI9
3MIA
3MY1
3TN8
3TNH
3TNI
4BCF
4BCG
4BCH
4BCI
4BCJ
4EC8
4EC9
4IMY
4OGR
4OR5
5L1Z
6CYT
6GZH
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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