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PURA and YBX1
Data Source:
HPRD
(in vivo, in vitro)
PURA
YBX1
Description
purine rich element binding protein A
Y-box binding protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Dendrite Cytoplasm
Neuronal Cell Body
Postsynapse
Glutamatergic Synapse
Extracellular Region
Nucleus
Nucleoplasm
U12-type Spliceosomal Complex
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Nuclear Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
CRD-mediated MRNA Stability Complex
Histone Pre-mRNA 3'end Processing Complex
Messenger Ribonucleoprotein Complex
Ribonucleoprotein Complex
Molecular Function
Translation Repressor Activity, MRNA Regulatory Element Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Double-stranded Telomeric DNA Binding
Single-stranded DNA Binding
RNA Binding
Protein Binding
Transcription Factor Binding
Purine-rich Negative Regulatory Element Binding
SMAD Binding
Nucleic Acid Binding
DNA Binding
Double-stranded DNA Binding
RNA Binding
Protein Binding
MiRNA Binding
GTPase Binding
C5-methylcytidine-containing RNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Translation
Cell Differentiation
Lymphocyte Proliferation
Epithelial Cell Proliferation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
MRNA Splicing, Via Spliceosome
Regulation Of Transcription, DNA-templated
Notch Signaling Pathway
Epidermis Development
Regulation Of Gene Expression
Negative Regulation Of Translation
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Stabilization
Embryonic Morphogenesis
RNA Transport
TRNA Transport
Positive Regulation Of Cell Division
CRD-mediated MRNA Stabilization
Protein Localization To Cytoplasmic Stress Granule
MiRNA Transport
Negative Regulation Of Cellular Senescence
Pathways
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Noncanonical activation of NOTCH3
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
57 interacting genes:
ADAP1
CCNT1
CDK5
E2F1
IL7R
MIR1-1
MIR106B
MIR122
MIR128-1
MIR128-2
MIR140
MIR143
MIR155
MIR15B
MIR16-2
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR205
MIR20B
MIR21
MIR221
MIR222
MIR25
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR7-1
MIR7-2
MIR9-2
MIR92A2
MIR93
MIRLET7A1
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PTEN
PURB
RAF1
RB1
SP1
YBX1
116 interacting genes:
ACTA2
AKT1
ANKRD2
APBB1
CALM1
CASP8
CSNK2A1
CTCF
DUX4
FBXO33
FMR1
FUS
GSK3B
H1-2
HABP4
HLA-C
HNRNPD
HNRNPK
IL7R
IREB2
IRF1
JAM2
LCP2
LSM3
MAPK1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYC
MYCN
NFYB
PCBP2
PCNA
PRPF40A
PURA
RBBP6
RPS6KA1
RPS6KA3
SLC6A4
SMAD3
SMU1
SREK1
SRSF9
TFAP2A
TP53
TRAF6
VEGFA
Entrez ID
5813
4904
HPRD ID
02721
01095
Ensembl ID
ENSG00000185129
ENSG00000065978
Uniprot IDs
Q00577
P67809
PDB IDs
1H95
5YTS
5YTT
5YTV
5YTX
6A6L
6KTC
6KUG
6LMR
6LMS
Enriched GO Terms of Interacting Partners
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