MIRLET7C and TUT4

Data Source:
BioGRID (unspecified method)

		MIRLET7C	TUT4
Description		microRNA let-7c	terminal uridylyl transferase 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Extracellular Exosome Extracellular Vesicle	Extracellular Space Nucleolus Cytoplasm Cytosol Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding Zinc Ion Binding Nucleotidyltransferase Activity MiRNA Binding RNA Uridylyltransferase Activity
	Biological Process	Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-8 Production Gene Silencing By MiRNA Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT	Nuclear-transcribed MRNA Poly(A) Tail Shortening Oocyte Maturation Negative Regulation Of Transposition, RNA-mediated MiRNA Metabolic Process MiRNA Catabolic Process Stem Cell Population Maintenance Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process RNA 3' Uridylation Polyuridylation-dependent MRNA Catabolic Process
Pathways			Deadenylation of mRNA
Drugs
Diseases
GWAS
Interacting Genes		96 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CHERP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RBMS2 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	10 interacting genes: MIR143 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		406885	23318
HPRD ID			15700
Ensembl ID		ENSG00000199030	ENSG00000134744
Uniprot IDs			A0A0C4DFM7 Q5TAX3
PDB IDs			6IW6
Enriched GO Terms of Interacting Partners?
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