CWC22 and KLHL2

Data Source:
BioGRID (two hybrid)

		CWC22	KLHL2
Description		CWC22 spliceosome associated protein homolog	kelch like family member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Nuclear Speck U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	RNA Binding Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome	Protein Ubiquitination Post-translational Protein Modification
Pathways		mRNA Splicing - Major Pathway	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28892062) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Schizophrenia ( 30285260)	Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		4 interacting genes: EIF4A3 EXOSC8 KLHL2 PTPN21	31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114
Entrez ID		57703	11275
HPRD ID		17220	09311
Ensembl ID		ENSG00000163510	ENSG00000109466
Uniprot IDs		Q9HCG8	B4DFZ5 E9PEX9 O95198
PDB IDs		4C9B 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF7 6ICZ 6QDV 6YVH 6ZYM 7A5P	2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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