KLHL2 and TMA16

		KLHL2	TMA16
Description		kelch like family member 2	translation machinery associated 16 homolog
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GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)	Small cell lung carcinoma ( 28604730)
Interacting Genes		31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114	8 interacting genes: AP2M1 APP CASTOR1 IKBKG KLHL2 KRTAP10-7 NEDD4L TSPYL2
Entrez ID		11275	55319
HPRD ID		09311	07739
Ensembl ID		ENSG00000109466	ENSG00000198498
Uniprot IDs		B4DFZ5 E9PEX9 O95198	Q96EY4
PDB IDs		2XN4 4CHB	6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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