SHTN1 and LNX2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		SHTN1	LNX2
Description		shootin 1	ligand of numb-protein X 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Lamellipodium Filopodium Axon Growth Cone Cell Leading Edge Perikaryon Axonal Growth Cone Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Kinesin Binding Cadherin Binding Actin Filament Binding	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Axonogenesis Cdc42 Protein Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Cytoplasmic Actin-based Contraction Involved In Cell Motility Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Regulation Of Establishment Of Cell Polarity Positive Regulation Of Neuron Migration
Pathways		Recycling pathway of L1
Drugs
Diseases
GWAS		Lysophosphatidylethanolamine levels ( 31551469)	Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		15 interacting genes: BBOX1 ESRRG EXOC6B FABP3 IGL IKBKG LNX1 LNX2 MEGF10 NEDD4 NME7 TFCP2 TNIP1 TP53BP2 ZCCHC17	89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581
Entrez ID		57698	222484
HPRD ID		11155	10042
Ensembl ID		ENSG00000187164	ENSG00000139517
Uniprot IDs		A0MZ66	Q8N448
PDB IDs			2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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