LNX2 and IP6K2

Data Source:
BioGRID (two hybrid)

		LNX2	IP6K2
Description		ligand of numb-protein X 2	inositol hexakisphosphate kinase 2
Image			No pdb structure
GO Annotations	Cellular Component		Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cell Junction
	Molecular Function	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Inositol Hexakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Flavonoid Binding
	Biological Process		Phosphate Ion Transport Negative Regulation Of Cell Growth Inositol Phosphate Biosynthetic Process Positive Regulation Of Apoptotic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Type I Interferon Signaling Pathway Cellular Response To Flavonoid
Pathways			Synthesis of IPs in the nucleus Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Adult body size ( 32376654) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Diastolic blood pressure ( 27841878) Eosinophil counts ( 32888494) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Morning person ( 30696823) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827)
Interacting Genes		89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	7 interacting genes: HSP90AA1 LNX2 MEOX2 PLOD3 PLSCR1 RBPMS ZBTB2
Entrez ID		222484	51447
HPRD ID		10042	07380
Ensembl ID		ENSG00000139517	ENSG00000068745
Uniprot IDs		Q8N448	A8K636 B2RCP4 Q9UHH9
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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