LNX2 and PARVG

Data Source:
BioGRID (two hybrid)

		LNX2	PARVG
Description		ligand of numb-protein X 2	parvin gamma
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton
	Molecular Function	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Actin Binding Protein Binding
	Biological Process		Cell-matrix Adhesion Establishment Or Maintenance Of Cell Polarity Cell Projection Assembly Actin Cytoskeleton Reorganization Substrate Adhesion-dependent Cell Spreading
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Metabolite levels ( 23823483) Survival in colon cancer ( 25866641)
Interacting Genes		89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	33 interacting genes: ALX4 ANTKMT APP CDHR3 CDSN CFAP53 CSF3 DDIT4L FOSL1 GADD45A HOMEZ ILK KCTD7 KLHL32 LHX3 LNX2 MEOX1 MEOX2 NBPF22P NBPF6 NDEL1 PDLIM7 POLR2G POU6F2 REL SERTAD2 TLE5 TRIB2 TRIM54 TSGA10IP USHBP1 ZNF426 ZNF677
Entrez ID		222484	64098
HPRD ID		10042	16285
Ensembl ID		ENSG00000139517	ENSG00000138964
Uniprot IDs		Q8N448	A0A024R4U4 Q9HBI0
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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