LNX2 and YJU2

Data Source:
BioGRID (two hybrid)

		LNX2	YJU2
Description		ligand of numb-protein X 2	YJU2 splicing factor homolog
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GO Annotations	Cellular Component		U2-type Catalytic Step 1 Spliceosome
	Molecular Function	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process		Generation Of Catalytic Spliceosome For First Transesterification Step RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	22 interacting genes: BANP BRAP CCDC57 CEP70 EMILIN1 FRS2 GAS8 GOLGA2 GOLGA6A JADE1 KAT5 LNX2 MAD1L1 MEOX2 REL TFCP2 TRIM15 TRIM21 TRIM27 ZNF143 ZNF526 ZNF829
Entrez ID		222484	55702
HPRD ID		10042	08546
Ensembl ID		ENSG00000139517	ENSG00000105248
Uniprot IDs		Q8N448	Q9BW85
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22	5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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