LRRC7 and CTNND2

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		LRRC7	CTNND2
Description		leucine rich repeat containing 7	catenin delta 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Centrosome Cytosol Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Cell Junction Specific Granule Lumen Axon Initial Segment	Nucleus Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Dendrite Perikaryon
	Molecular Function	Protein Binding	Protein Binding Beta-catenin Binding Cadherin Binding
	Biological Process	MAPK Cascade Embryo Development Positive Regulation Of Neuron Projection Development Receptor Clustering Neutrophil Degranulation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Cell-cell Adhesion Regulation Of NMDA Receptor Activity	Cell-cell Junction Assembly Cell Adhesion Signal Transduction Wnt Signaling Pathway Synapse Organization Regulation Of Canonical Wnt Signaling Pathway Dendritic Spine Morphogenesis Cell-cell Adhesion
Pathways
Drugs
Diseases			Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 21784300) Body mass index ( 24348519) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666) Psoriasis ( 25939698) Type 2 diabetes ( 31049640)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cannabis dependence symptom count ( 27028160) Cognitive performance (processing speed) ( 31598132) Common carotid intima-media thickness in HIV infection ( 29206233) Corneal astigmatism ( 30306274) Facial emotion recognition ( 28608620) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lewy body disease ( 25188341) Macular thickness ( 30535121) Myopia (pathological) ( 21095009) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to antidepressants (symptom improvement) ( 29160301) Sensorimotor dexterity ( 31596458) Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 27841878) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		17 interacting genes: ACTN2 ACTN4 ADGRB1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 EPS15L1 ERBB2 ERBB3 ERBB4 HOMER3 HOMEZ NQO2 PPP1R9B TOR1A	20 interacting genes: ABL1 ATN1 CDH1 CDH2 CLK1 CTNNB1 CTTN ERBIN FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 PTGER4 SPHK1 TTR
Entrez ID		57554	1501
HPRD ID		09930	09181
Ensembl ID		ENSG00000033122	ENSG00000169862
Uniprot IDs		A0A075B6E9	B4DJU1 B4DRK2 E7EPC8 Q9UQB3
PDB IDs
Enriched GO Terms of Interacting Partners?
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