LRRC7 and ADGRB1

Data Source:
BioGRID (unspecified method)

		LRRC7	ADGRB1
Description		leucine rich repeat containing 7	adhesion G protein-coupled receptor B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Centrosome Cytosol Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Cell Junction Specific Granule Lumen Axon Initial Segment	Phagocytic Cup Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Postsynaptic Density Integral Component Of Membrane Dendrite Dendritic Spine Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Lipopolysaccharide Binding Phosphatidylserine Binding G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding
	Biological Process	MAPK Cascade Embryo Development Positive Regulation Of Neuron Projection Development Receptor Clustering Neutrophil Degranulation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Cell-cell Adhesion Regulation Of NMDA Receptor Activity	Phagocytosis, Recognition Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Peripheral Nervous System Development Muscle Organ Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Innate Immune Response Regulation Of Synaptic Plasticity Defense Response To Gram-negative Bacterium Positive Regulation Of Synapse Assembly Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 21784300) Body mass index ( 24348519) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666) Psoriasis ( 25939698) Type 2 diabetes ( 31049640)
Interacting Genes		17 interacting genes: ACTN2 ACTN4 ADGRB1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 EPS15L1 ERBB2 ERBB3 ERBB4 HOMER3 HOMEZ NQO2 PPP1R9B TOR1A	21 interacting genes: BAIAP2 BAIAP3 DLG1 DLG4 DRD2 ELMO1 ERBB2 GPR35 GPR37 LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PATJ PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2
Entrez ID		57554	575
HPRD ID		09930	04062
Ensembl ID		ENSG00000033122	ENSG00000181790
Uniprot IDs		A0A075B6E9	O14514
PDB IDs
Enriched GO Terms of Interacting Partners?
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