CTNND2 and PDZD2

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		CTNND2	PDZD2
Description		catenin delta 2	PDZ domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Dendrite Perikaryon	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Cell-cell Junction Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding
	Biological Process	Cell-cell Junction Assembly Cell Adhesion Signal Transduction Wnt Signaling Pathway Synapse Organization Regulation Of Canonical Wnt Signaling Pathway Dendritic Spine Morphogenesis Cell-cell Adhesion	Cell Adhesion
Pathways
Drugs
Diseases		Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cannabis dependence symptom count ( 27028160) Cognitive performance (processing speed) ( 31598132) Common carotid intima-media thickness in HIV infection ( 29206233) Corneal astigmatism ( 30306274) Facial emotion recognition ( 28608620) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lewy body disease ( 25188341) Macular thickness ( 30535121) Myopia (pathological) ( 21095009) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to antidepressants (symptom improvement) ( 29160301) Sensorimotor dexterity ( 31596458) Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 27841878) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Chronic obstructive pulmonary disease ( 29394082) Corpus callosum central volume ( 31530798) Height ( 28552196) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) Myocardial infarction ( 26708285) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Renal cell carcinoma ( 23184150) Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284) Reticulocyte fraction of red cells ( 32888494) Self-reported childhood asthma in adult smokers ( 30373671) Vertical cup-disc ratio ( 31798171 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Working memory ( 31598132)
Interacting Genes		20 interacting genes: ABL1 ATN1 CDH1 CDH2 CLK1 CTNNB1 CTTN ERBIN FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 PTGER4 SPHK1 TTR	5 interacting genes: ADGRB1 CST3 CTNND2 NRXN1 PKP4
Entrez ID		1501	23037
HPRD ID		09181	10142
Ensembl ID		ENSG00000169862	ENSG00000133401
Uniprot IDs		B4DJU1 B4DRK2 E7EPC8 Q9UQB3	A0A024RE15 O15018
PDB IDs
Enriched GO Terms of Interacting Partners?
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