SCYL1 and CHD1L

Data Source:
BioGRID (two hybrid)

		SCYL1	CHD1L
Description		SCY1 like pseudokinase 1	chromodomain helicase DNA binding protein 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Microtubule Organizing Center Cytosol Membrane COPI Vesicle Coat	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	DNA Binding Protein Tyrosine Kinase Activity ATP Binding Cadherin Binding	Nucleotide Binding DNA Helicase Activity Protein Binding ATP Binding ATPase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Inflammatory Response Peptidyl-tyrosine Phosphorylation Spinal Cord Motor Neuron Differentiation Cellular Protein Localization Neuron Development	Nucleotide-excision Repair, DNA Duplex Unwinding DNA Repair Nucleotide-excision Repair, Preincision Complex Stabilization Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Chromatin Remodeling Cellular Response To DNA Damage Stimulus Nucleotide-excision Repair, DNA Incision Global Genome Nucleotide-excision Repair
Pathways			Formation of Incision Complex in GG-NER Dual Incision in GG-NER
Drugs		Grn163l
Diseases
GWAS		Acne (severe) ( 24927181) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femoral neck bone mineral density ( 22504420) Refractive error ( 32231278) Vertical cup-disc ratio ( 20548946)	Height ( 31562340) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25760438)
Interacting Genes		23 interacting genes: APP ARCN1 ARF1 ARF3 AXIN1 CCNF CD93 CDC25A CHD1L COIL COPA COPB1 COPE COPG1 DAPK1 DDX6 GORAB LENG1 NOD2 PIN1 PLEKHF2 SMURF1 TCEA2	5 interacting genes: BAALC CTCF NR4A1 SCYL1 SRPK2
Entrez ID		57410	9557
HPRD ID		06414	09880
Ensembl ID		ENSG00000142186	ENSG00000131778
Uniprot IDs		E9PK59 Q96KG9	A0A0A0MRH8 A0A0A0MSH9 Q86WJ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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