SCYL1 and LENG1

Data Source:
BioGRID (two hybrid)

		SCYL1	LENG1
Description		SCY1 like pseudokinase 1	leukocyte receptor cluster member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Microtubule Organizing Center Cytosol Membrane COPI Vesicle Coat	Cellular_component
	Molecular Function	DNA Binding Protein Tyrosine Kinase Activity ATP Binding Cadherin Binding	Molecular_function Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Inflammatory Response Peptidyl-tyrosine Phosphorylation Spinal Cord Motor Neuron Differentiation Cellular Protein Localization Neuron Development	Biological_process
Pathways
Drugs		Grn163l
Diseases
GWAS		Acne (severe) ( 24927181) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femoral neck bone mineral density ( 22504420) Refractive error ( 32231278) Vertical cup-disc ratio ( 20548946)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		23 interacting genes: APP ARCN1 ARF1 ARF3 AXIN1 CCNF CD93 CDC25A CHD1L COIL COPA COPB1 COPE COPG1 DAPK1 DDX6 GORAB LENG1 NOD2 PIN1 PLEKHF2 SMURF1 TCEA2	84 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP57L1 CEP70 DDIT4L DES DISC1 EVI5 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 ZMYND12 ZRANB1
Entrez ID		57410	79165
HPRD ID		06414	13985
Ensembl ID		ENSG00000142186	ENSG00000105617
Uniprot IDs		E9PK59 Q96KG9	Q96BZ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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