SCYL1 and CD93

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid)

		SCYL1	CD93
Description		SCY1 like pseudokinase 1	CD93 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Microtubule Organizing Center Cytosol Membrane COPI Vesicle Coat	Plasma Membrane Cell Surface Integral Component Of Membrane Secretory Granule Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	DNA Binding Protein Tyrosine Kinase Activity ATP Binding Cadherin Binding	Complement Component C1q Complex Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Inflammatory Response Peptidyl-tyrosine Phosphorylation Spinal Cord Motor Neuron Differentiation Cellular Protein Localization Neuron Development	Phagocytosis Viral Process Macrophage Activation Neutrophil Degranulation Cell-cell Adhesion
Pathways			Neutrophil degranulation
Drugs		Grn163l
Diseases
GWAS		Acne (severe) ( 24927181) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femoral neck bone mineral density ( 22504420) Refractive error ( 32231278) Vertical cup-disc ratio ( 20548946)	Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)
Interacting Genes		23 interacting genes: APP ARCN1 ARF1 ARF3 AXIN1 CCNF CD93 CDC25A CHD1L COIL COPA COPB1 COPE COPG1 DAPK1 DDX6 GORAB LENG1 NOD2 PIN1 PLEKHF2 SMURF1 TCEA2	23 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2
Entrez ID		57410	22918
HPRD ID		06414	00396
Ensembl ID		ENSG00000142186	ENSG00000125810
Uniprot IDs		E9PK59 Q96KG9	Q9NPY3
PDB IDs
Enriched GO Terms of Interacting Partners?
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