ANKS1B and NCK2

  • Data Source:
  • BioGRID (two hybrid)

ANKS1B

NCK2

Description ankyrin repeat and sterile alpha motif domain containing 1B NCK adaptor protein 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Angiotensin-converting enzyme inhibitor intolerance ( 28030426)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Body fat percentage ( 31752434)
  • Body mass index ( 20966902)
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Body size at age 10 ( 32376654)
  • Electrodermal activity ( 25387706)
  • Left-handedness ( 32989287)
  • Metabolite levels (HVA/5-HIAA ratio) ( 23319000)
  • Obesity-related traits ( 23251661)
  • Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627)
  • Response to antipsychotic treatment ( 19721433)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)
  • Waist circumference ( 20966902)
Interacting Genes 13 interacting genes: APP CASS4 EGFR ERBB2 ERBB4 HSF2BP HTR2A LRP1 LRP2 NCK2 RHOA RIN1 UBC 171 interacting genes: ABI1 ABI2 ABI3 ANKRD55 ANKS1B ARHGAP32 ATN1 AXIN1 AXL BCAR1 BCL11A BTG1 C4orf17 CBARP CBLB CCDC120 CCDC33 CD3E CHN1 CHN2 CIB1 CIPC CLEC17A CPSF6 CPSF7 CUEDC1 DDR1 DEFB124 DISC1 DLGAP4 DNM1 DOCK1 DOK1 DRAP1 DTX3 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EFS EGFR EIF3H ERBB2 ERBB3 ERBB4 FAM124A FAM47A FAM53C FAM83A FASLG FBXL19 FCRL2 FGFR1 FOSB FXR2 FYB1 GAB1 GAREM1 GGN HNRNPK HOMEZ HOXA1 HOXC4 HOXD8 HSF2BP ILK INCA1 INTS2 IRS1 KCTD17 KHDRBS1 KIAA0408 KIAA1217 KIT KLHL24 KLHL35 KPRP LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MBD6 MEOX2 MET MIA3 MNT MYPOP NCKIPSD NELFA NET1 NFKBID NHSL2 NPAS2 NPHS1 NR5A1 NTRK2 NUTM2F ONECUT3 PAK1 PAK2 PBX4 PDGFRB PHETA1 PIK3AP1 PKD1 PKN2 PRDM6 PRR16 PRR20A PRR20B PRR20C PRR20D PRR20E PSMD10 PTK2 RASSF7 RBBP8NL RBM26 REEP4 REL SCML2 SCX SF1 SF3A2 SF3B4 SHD SKAP2 SMARCB1 SNW1 SOCS7 SORBS2 SOS1 SPATA2L SPATC1L SPRY2 SRMS SRPK1 SRPK2 SSH3 SYNGAP1 SYNPO TCF4 TCP10L TMEM121 TNR TRIM27 TRIM41 TRIP6 TXK UBC USP32 VARS2 VPS37B WAS WASF1 WASL WBP11 WIPF1 WIPF2 ZBTB12 ZBTB42 ZBTB7B ZC2HC1A ZC2HC1B ZNF341 ZNF526 ZNF688
Entrez ID 56899 8440
HPRD ID 07426 05378
Ensembl ID ENSG00000185046 ENSG00000071051
Uniprot IDs B1VKB5 B7Z9I9 Q6V0K8 Q7Z6G8 A0A0S2Z4M6 E7ERP6 O43639
PDB IDs 2EAM 2KE7 2KIV 2M38 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R
Enriched GO Terms of Interacting Partners?
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