ANKS1B and LRP1

  • Data Source:
  • BioGRID (two hybrid)

ANKS1B

LRP1

Description ankyrin repeat and sterile alpha motif domain containing 1B LDL receptor related protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Angiotensin-converting enzyme inhibitor intolerance ( 28030426)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Body fat percentage ( 31752434)
  • Body mass index ( 20966902)
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Body size at age 10 ( 32376654)
  • Electrodermal activity ( 25387706)
  • Left-handedness ( 32989287)
  • Metabolite levels (HVA/5-HIAA ratio) ( 23319000)
  • Obesity-related traits ( 23251661)
  • Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627)
  • Response to antipsychotic treatment ( 19721433)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)
  • Waist circumference ( 20966902)
Interacting Genes 13 interacting genes: APP CASS4 EGFR ERBB2 ERBB4 HSF2BP HTR2A LRP1 LRP2 NCK2 RHOA RIN1 UBC 70 interacting genes: A2M ANAPC10 ANKS1B APBA2 APBB1 APOE APP BACE1 BDNF C3 C4BPA CACNA1A CALR CANX CAV1 CC2D1A CCN2 CD82 CTSG DAB1 DAB2 DLG4 EGFR ELANE F8 F9 FURIN GIPC1 GTPBP1 GULP1 HNRNPDL HSP90B1 ITGB1BP1 KAT5 LIPC LPL LRPAP1 LTF MAPK8IP1 MAPK8IP2 MAPRE1 MDK MMP13 MMP14 MMP15 MMP16 MMP17 MTDH NGF NOS1AP NTF3 NTF4 PDGFB PID1 PLAT PLAUR PRKACA PTPN11 RIC8B SCN3A SERPINA1 SERPINE1 SHC1 SKIL SNRNP70 SNX17 SRC SYNJ2BP THBS1 WNT3A
Entrez ID 56899 4035
HPRD ID 07426 00138
Ensembl ID ENSG00000185046 ENSG00000123384
Uniprot IDs B1VKB5 B7Z9I9 Q6V0K8 Q7Z6G8 Q07954 Q59FG2
PDB IDs 2EAM 2KE7 2KIV 2M38 1CR8 1D2L 1J8E 2FYJ 2FYL 2KNX 2KNY
Enriched GO Terms of Interacting Partners?
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