ANKS1B and LRP2

  • Data Source:
  • HPRD (two hybrid)

ANKS1B

LRP2

Description ankyrin repeat and sterile alpha motif domain containing 1B LDL receptor related protein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Angiotensin-converting enzyme inhibitor intolerance ( 28030426)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Body fat percentage ( 31752434)
  • Body mass index ( 20966902)
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Body size at age 10 ( 32376654)
  • Electrodermal activity ( 25387706)
  • Left-handedness ( 32989287)
  • Metabolite levels (HVA/5-HIAA ratio) ( 23319000)
  • Obesity-related traits ( 23251661)
  • Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627)
  • Response to antipsychotic treatment ( 19721433)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)
  • Waist circumference ( 20966902)
Interacting Genes 13 interacting genes: APP CASS4 EGFR ERBB2 ERBB4 HSF2BP HTR2A LRP1 LRP2 NCK2 RHOA RIN1 UBC 51 interacting genes: ALB ANAPC10 ANKRA2 ANKS1B APBA2 APBB1 APOB APOE APOH APP ATN1 CDC42 CLU CUBN DAB1 DAB2 DLG1 DLG2 DLG3 DLG4 GC GIPC1 GPRASP1 INS ITGB1BP1 LCN2 LDLRAP1 LPA LPL LRP2BP LRPAP1 MAGI1 MAPK8IP1 MAPK8IP2 MDK NOS1AP PIP5K1C PLAU RAC1 RBP1 RHOA SCGB1A1 SCN3A SERPINE1 SLC9A3 SNX17 SYNJ2BP TG THBS1 TLN1 TTR
Entrez ID 56899 4036
HPRD ID 07426 02509
Ensembl ID ENSG00000185046 ENSG00000081479
Uniprot IDs B1VKB5 B7Z9I9 Q6V0K8 Q7Z6G8 P98164 Q7Z5C0 Q7Z5C1
PDB IDs 2EAM 2KE7 2KIV 2M38 2M0P
Enriched GO Terms of Interacting Partners?
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