RETN and GPR25

Data Source:
BioGRID (two hybrid)

		RETN	GPR25
Description		resistin	G protein-coupled receptor 25
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Signal Transduction Aging Biological_process Response To Mechanical Stimulus Response To Insulin Neutrophil Degranulation Fat Cell Differentiation Positive Regulation Of Synaptic Transmission Negative Regulation Of Feeding Behavior Positive Regulation Of Progesterone Secretion	G Protein-coupled Receptor Signaling Pathway
Pathways		Neutrophil degranulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Menarche (age at onset) ( 25231870) Resistin levels ( 27664181 24123702 22843503)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: A2M GPR25 SF3A2	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		56729	2848
HPRD ID		05714	03707
Ensembl ID		ENSG00000104918	ENSG00000170128
Uniprot IDs		Q9HD89	O00155
PDB IDs		1LV6
Enriched GO Terms of Interacting Partners?
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