GPR25 and RETN

Data Source:
BioGRID (two hybrid)

		GPR25	RETN
Description		G protein-coupled receptor 25	resistin
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Nucleus Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Hormone Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Signal Transduction Aging Biological_process Response To Mechanical Stimulus Response To Insulin Neutrophil Degranulation Fat Cell Differentiation Positive Regulation Of Synaptic Transmission Negative Regulation Of Feeding Behavior Positive Regulation Of Progesterone Secretion
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Neutrophil degranulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)	Blood protein levels ( 30072576 29875488) Menarche (age at onset) ( 25231870) Resistin levels ( 27664181 24123702 22843503)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	3 interacting genes: A2M GPR25 SF3A2
Entrez ID		2848	56729
HPRD ID		03707	05714
Ensembl ID		ENSG00000170128	ENSG00000104918
Uniprot IDs		O00155	Q9HD89
PDB IDs			1LV6
Enriched GO Terms of Interacting Partners?
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