RETN and SF3A2

Data Source:
HPRD (in vitro)

		RETN	SF3A2
Description		resistin	splicing factor 3a subunit 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Hormone Activity Protein Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Signal Transduction Aging Biological_process Response To Mechanical Stimulus Response To Insulin Neutrophil Degranulation Fat Cell Differentiation Positive Regulation Of Synaptic Transmission Negative Regulation Of Feeding Behavior Positive Regulation Of Progesterone Secretion	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Positive Regulation Of Neuron Projection Development U2-type Prespliceosome Assembly
Pathways		Neutrophil degranulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	mRNA Splicing - Major Pathway
Drugs			Copper
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Menarche (age at onset) ( 25231870) Resistin levels ( 27664181 24123702 22843503)	Adult body size ( 32376654) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Myocardial infarction ( 24916648) Pulse pressure ( 26390057)
Interacting Genes		3 interacting genes: A2M GPR25 SF3A2	20 interacting genes: APBB1 ASPH BAIAP2 BEND2 CDC42 GRB2 HTATSF1 LIN54 NCK2 OSTF1 PRPF40A RETN SF3A1 SH3RF1 SMURF2 TCERG1 TFG TRIP10 VEZF1 YY1
Entrez ID		56729	8175
HPRD ID		05714	02877
Ensembl ID		ENSG00000104918	ENSG00000104897
Uniprot IDs		Q9HD89	Q05DF2 Q15428
PDB IDs		1LV6	5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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