PRKCG and HABP4

Data Source:
HPRD (in vivo, in vitro)

		PRKCG	HABP4
Description		protein kinase C gamma	hyaluronan binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Cell-cell Junction Postsynaptic Density Dendrite Calyx Of Held Perinuclear Region Of Cytoplasm Synaptic Membrane Presynaptic Cytosol Postsynaptic Cytosol	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Stress Granule Cajal Body Sarcoplasm Nuclear Speck Sarcomere Gemini Of Coiled Bodies
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding	RNA Binding Protein Binding SUMO Binding
	Biological Process	Protein Phosphorylation Chemical Synaptic Transmission Learning Or Memory Chemosensory Behavior Phosphorylation Peptidyl-serine Phosphorylation Platelet Activation Negative Regulation Of Protein Ubiquitination Regulation Of Response To Food Positive Regulation Of Mismatch Repair Intracellular Signal Transduction Negative Regulation Of Protein Catabolic Process Regulation Of Circadian Rhythm Response To Morphine Negative Regulation Of Neuron Apoptotic Process Protein Autophosphorylation Response To Pain Rhythmic Process Regulation Of Phagocytosis Innervation Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Proteasomal Protein Catabolic Process Response To Psychosocial Stress Regulation Of Synaptic Vesicle Exocytosis	Platelet Degranulation MRNA Processing RNA Splicing PML Body Organization Positive Regulation Of RNA Splicing Negative Regulation Of DNA Binding Positive Regulation Of Translational Initiation Cellular Response To Mechanical Stimulus
Pathways		Calmodulin induced events Disinhibition of SNARE formation Trafficking of GluR2-containing AMPA receptors G alpha (z) signalling events WNT5A-dependent internalization of FZD4 Response to elevated platelet cytosolic Ca2+	Platelet degranulation
Drugs		Tamoxifen Fostamatinib	Hyaluronic acid
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Height ( 25282103 31562340) Household income (MTAG) ( 31844048)
Interacting Genes		64 interacting genes: AFAP1 ANXA7 APP ARHGEF25 ARHGEF7 CASR CCHCR1 CD5 CDC42 CHAT CTNNB1 CYTH2 DAB2 DDX58 DNAJC5 DVL2 EIF4E EPHB1 EXOC5 FBXO7 GABRA1 GABRA4 GFAP GJA1 GJA3 GRIA4 GRIN1 GRIN2B GRIN2D GRK2 GRM5 GSK3A HABP4 HSPA4 IRS1 ITGB2 MAPT MARK4 NOXA1 NRGN NUMB PA2G4 PARD3 PARD6A PARD6B PDLIM5 PEBP1 PICK1 PNMA1 PPP1R14A RANBP10 RGS2 SCN3A SDC2 SMURF1 STXBP1 TIAM1 TOP2A TRIM5 UBE2T VTN YWHAB YWHAE YWHAG	25 interacting genes: C1QBP CHD3 CRK DAXX ENO2 FRA10AC1 HMGXB4 KAT5 PIAS3 PPP1R15A PRKCA PRKCB PRKCD PRKCG PRKCQ PRKCZ PRMT1 RACK1 SRSF9 SYNCRIP TOPORS TP53 UBE2I VIM YBX1
Entrez ID		5582	22927
HPRD ID		01502	13628
Ensembl ID		ENSG00000126583	ENSG00000130956
Uniprot IDs		B2R5T1 B7Z3W6 P05129	Q5JVS0
PDB IDs		2E73 2UZP
Enriched GO Terms of Interacting Partners?
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