PRKAR1B and ZNF410

Data Source:
BioGRID (two hybrid)

		PRKAR1B	ZNF410
Description		protein kinase cAMP-dependent type I regulatory subunit beta	zinc finger protein 410
Image			No pdb structure
GO Annotations	Cellular Component	Multivesicular Body Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Ciliary Base Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse	Nucleus
	Molecular Function	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity CAMP Binding Protein Kinase A Catalytic Subunit Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Renal Water Homeostasis Protein Phosphorylation Blood Coagulation Learning Or Memory Regulation Of Protein Kinase A Signaling Activation Of Protein Kinase A Activity Regulation Of CAMP-mediated Signaling Modulation Of Chemical Synaptic Transmission Cellular Response To Glucagon Stimulus Regulation Of Synaptic Vesicle Cycle Negative Regulation Of CAMP-dependent Protein Kinase Activity	Regulation Of Transcription By RNA Polymerase II
Pathways		PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Plasma free amino acid levels ( 30659259) Red blood cell count ( 32888494 27863252)	Blood protein levels ( 28240269) Serum uric acid levels ( 29559957)
Interacting Genes		76 interacting genes: AKAP1 AKAP14 AKAP7 ANKS1A BAG3 BAG6 BOD1L2 CAMSAP1 CBX8 CCDC103 CCDC187 CDC37 CDKN1A CEP19 COX5B DACH1 DTNB EEF2KMT EGFR FAM161A FAM90A1 FCHSD2 GAS2L2 GLIS2 GNL3L GOLGA1 GPKOW GUCA1A IGFN1 INPP5J KANK2 KIF5B L3MBTL2 LENG1 LNX1 MBD3 MED8 MYO15B NTAQ1 NXF1 PIK3R3 POLE4 PPP1R9A PRKAA2 PRKACA PRKAR1A PRPF18 PSMG1 QRICH1 RARG RUNX1T1 SAP30BP SH2D4A SHC3 SMAD3 SMAD4 SMG9 SNW1 STK16 SYTL4 TASOR2 TEAD4 THRA TSGA10IP UACA VEZF1 WNK1 WRN ZBTB16 ZMYND19 ZNF177 ZNF329 ZNF35 ZNF410 ZNF559-ZNF177 ZNF76	54 interacting genes: ABHD8 APP BANP BLZF1 CCNG2 CDKN2A CEP70 CSNK2B DPEP2NB DVL2 FAM9B FHL2 FSD2 GOLGA2 GOLGA6L9 HOXB2 IQUB IRAK1BP1 KRT40 LIMS1 LMO2 LMO4 LNX2 LRIF1 MEOX1 MEOX2 MID2 MTUS2 NDUFAB1 NOSIP OSM PAX6 PDE4DIP PICK1 PNMA1 POGZ POLR2G POLR2M POU6F2 PPM1K PPP1R16B PRKAR1B RAB3IP RASSF3 RCN1 RPRD1A SERTAD1 TRAF2 TRIM35 TSGA10 UHRF2 VBP1 ZNF24 ZNF397
Entrez ID		5575	57862
HPRD ID		01485	18339
Ensembl ID		ENSG00000188191	ENSG00000119725
Uniprot IDs		P31321	A0A024R691 Q53FM1 Q86VK4
PDB IDs		4DIN 4F9K
Enriched GO Terms of Interacting Partners?
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