ZNF410 and UHRF2

Data Source:
BioGRID (two hybrid)

		ZNF410	UHRF2
Description		zinc finger protein 410	ubiquitin like with PHD and ring finger domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Heterochromatin Nucleus Nucleoplasm Pericentric Heterochromatin
	Molecular Function	Transcription Coregulator Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Histone Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Cell Cycle Maintenance Of DNA Methylation Protein Ubiquitination Cell Differentiation Regulation Of Cell Cycle Protein Autoubiquitination Positive Regulation Of Cell Cycle Arrest
Pathways			SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Serum uric acid levels ( 29559957)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Periodontal microbiota ( 22699663)
Interacting Genes		54 interacting genes: ABHD8 APP BANP BLZF1 CCNG2 CDKN2A CEP70 CSNK2B DPEP2NB DVL2 FAM9B FHL2 FSD2 GOLGA2 GOLGA6L9 HOXB2 IQUB IRAK1BP1 KRT40 LIMS1 LMO2 LMO4 LNX2 LRIF1 MEOX1 MEOX2 MID2 MTUS2 NDUFAB1 NOSIP OSM PAX6 PDE4DIP PICK1 PNMA1 POGZ POLR2G POLR2M POU6F2 PPM1K PPP1R16B PRKAR1B RAB3IP RASSF3 RCN1 RPRD1A SERTAD1 TRAF2 TRIM35 TSGA10 UHRF2 VBP1 ZNF24 ZNF397	38 interacting genes: ATXN1 BAX BCAR1 BCL2L1 CCND1 CD27 CDK1 CDK2 CDK4 CDK6 CTNNB1 DESI1 FANCD2 FYN H3C1 JAK3 LCK LYN MCL1 PCNP PTPRC RAD51 RBCK1 RUNX1 SKP1 SMAD4 TP53 TRIM27 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2W UHRF1 YY1 ZNF410 ZNF618
Entrez ID		57862	115426
HPRD ID		18339	18257
Ensembl ID		ENSG00000119725	ENSG00000147854
Uniprot IDs		A0A024R691 Q53FM1 Q86VK4	Q96PU4
PDB IDs			1WY8 1Z6U 2E6S 3OLN 4PW5 4PW6 4PW7 4TVR 5YCO
Enriched GO Terms of Interacting Partners?
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