PRKAR1B and UACA

Data Source:
BioGRID (two hybrid)

		PRKAR1B	UACA
Description		protein kinase cAMP-dependent type I regulatory subunit beta	uveal autoantigen with coiled-coil domains and ankyrin repeats
Image			No pdb structure
GO Annotations	Cellular Component	Multivesicular Body Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Ciliary Base Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse	Extracellular Region Nucleus Nucleoplasm Cytosol Cytoskeleton Extracellular Exosome
	Molecular Function	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity CAMP Binding Protein Kinase A Catalytic Subunit Binding	Molecular_function Protein Binding
	Biological Process	Renal Water Homeostasis Protein Phosphorylation Blood Coagulation Learning Or Memory Regulation Of Protein Kinase A Signaling Activation Of Protein Kinase A Activity Regulation Of CAMP-mediated Signaling Modulation Of Chemical Synaptic Transmission Cellular Response To Glucagon Stimulus Regulation Of Synaptic Vesicle Cycle Negative Regulation Of CAMP-dependent Protein Kinase Activity	Biological_process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Apoptotic Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production	Regulation of the apoptosome activity
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Plasma free amino acid levels ( 30659259) Red blood cell count ( 32888494 27863252)	Atrial fibrillation ( 29892015) Pulmonary function ( 23932459)
Interacting Genes		76 interacting genes: AKAP1 AKAP14 AKAP7 ANKS1A BAG3 BAG6 BOD1L2 CAMSAP1 CBX8 CCDC103 CCDC187 CDC37 CDKN1A CEP19 COX5B DACH1 DTNB EEF2KMT EGFR FAM161A FAM90A1 FCHSD2 GAS2L2 GLIS2 GNL3L GOLGA1 GPKOW GUCA1A IGFN1 INPP5J KANK2 KIF5B L3MBTL2 LENG1 LNX1 MBD3 MED8 MYO15B NTAQ1 NXF1 PIK3R3 POLE4 PPP1R9A PRKAA2 PRKACA PRKAR1A PRPF18 PSMG1 QRICH1 RARG RUNX1T1 SAP30BP SH2D4A SHC3 SMAD3 SMAD4 SMG9 SNW1 STK16 SYTL4 TASOR2 TEAD4 THRA TSGA10IP UACA VEZF1 WNK1 WRN ZBTB16 ZMYND19 ZNF177 ZNF329 ZNF35 ZNF410 ZNF559-ZNF177 ZNF76	13 interacting genes: AHCYL1 ANKRD28 CCDC125 CELSR3 HIF1AN JPH1 KRT31 KRT40 MED14 PRKAR1B RTP2 STAMBP UBQLN2
Entrez ID		5575	55075
HPRD ID		01485	11657
Ensembl ID		ENSG00000188191	ENSG00000137831
Uniprot IDs		P31321	Q9BZF9
PDB IDs		4DIN 4F9K
Enriched GO Terms of Interacting Partners?
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