LYAR and BEND7

Data Source:
BioGRID (two hybrid)

		LYAR	BEND7
Description		Ly1 antibody reactive	BEN domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleus Nucleoplasm Nucleolus Cytoplasm	Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding Protein Binding Activating Transcription Factor Binding Identical Protein Binding Metal Ion Binding Transcription Regulator Inhibitor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RRNA Processing Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase I Erythrocyte Development Positive Regulation Of Phagocytosis
Pathways
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration ( 29346644)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Diastolic blood pressure ( 30224653) Free thyroxine concentration ( 30367059) Hematocrit ( 32888494) Hemoglobin ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900) Skin pigmentation ( 28300201) Smoking status (ever vs never smokers) ( 30643258) White blood cell count ( 32888494)
Interacting Genes		12 interacting genes: ADSS1 BEND7 CD2 FGF18 PHF20L1 PRKRA SDCBP2 SREK1IP1 TERF1 TERF2 ZBTB16 ZHX1	73 interacting genes: ANP32B BANF2 BYSL C14orf119 CDC37 CDCA7L CEP44 CHD2 CIB3 CSNK2A1 DDX6 DVL2 DVL3 EAF1 EAF2 EIF1AD EMD FAM124A FAM133A GADD45G GEMIN2 GTPBP3 GYS1 HMBOX1 HSF2BP KANK2 L3MBTL2 LMO3 LNX1 LYAR MAGOHB MFAP1 MLX MORF4L1 MORF4L2 MYO15B NAP1L3 NEK6 NIF3L1 NKAPD1 NOL12 NUTF2 OSGIN1 PBLD PIM1 PLEKHF2 POLR3GL PPIG PPP1R37 PRMT3 PRPF40A PSMB1 PSMF1 RAB29 RBM10 RIPPLY1 RPL22 SCNM1 SDCBP SDCBP2 SMARCA2 SPANXN2 THAP1 TLK1 TNPO2 TRIM26 U2AF2 UBL5 USP20 VCX2 WHRN ZCCHC10 ZNF622
Entrez ID		55646	222389
HPRD ID		10064	12570
Ensembl ID		ENSG00000145220	ENSG00000165626
Uniprot IDs		Q9NX58	Q8N7W2
PDB IDs		6ZMI 6ZMO 6ZVH
Enriched GO Terms of Interacting Partners?
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