LYAR and ADSS1

Data Source:
BioGRID (two hybrid)

		LYAR	ADSS1
Description		Ly1 antibody reactive	adenylosuccinate synthase 1
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleus Nucleoplasm Nucleolus Cytoplasm	Cytoplasm Cytosol
	Molecular Function	DNA Binding RNA Binding Protein Binding Activating Transcription Factor Binding Identical Protein Binding Metal Ion Binding Transcription Regulator Inhibitor Activity	Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity GTP Binding Phosphate Ion Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RRNA Processing Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase I Erythrocyte Development Positive Regulation Of Phagocytosis	Immune System Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Muscle Activity Cellular Response To Drug Response To Starvation 'de Novo' AMP Biosynthetic Process IMP Metabolic Process Cellular Response To Electrical Stimulus
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Aspartic acid Hadacidin 6-O-Phosphoryl Inosine Monophosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Adenylosuccinic acid Inosinic Acid Alanosine
Diseases
GWAS		Disease progression in age-related macular degeneration ( 29346644)
Interacting Genes		12 interacting genes: ADSS1 BEND7 CD2 FGF18 PHF20L1 PRKRA SDCBP2 SREK1IP1 TERF1 TERF2 ZBTB16 ZHX1	2 interacting genes: AZIN1 LYAR
Entrez ID		55646	122622
HPRD ID		10064	12433
Ensembl ID		ENSG00000145220	ENSG00000185100
Uniprot IDs		Q9NX58	B3KTV4 Q8N142
PDB IDs		6ZMI 6ZMO 6ZVH	2GJO
Enriched GO Terms of Interacting Partners?
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