VEZT and MYO7A

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		VEZT	MYO7A
Description		vezatin, adherens junctions transmembrane protein	myosin VIIA
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Stereocilia Ankle Link Complex Nucleoplasm Cytosol Adherens Junction Integral Component Of Membrane Stereocilium Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density
	Molecular Function	Myosin Binding	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding
	Biological Process	Cell-cell Adhesion	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization
Pathways			The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases			Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Brain morphology (MOSTest) ( 32665545) Endometriosis ( 23104006 23472165 28537267) Pursuit maintenance gain ( 29064472)	Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)
Interacting Genes		16 interacting genes: ANKS6 AQP6 C5 CMTM3 CREB3L1 GORAB HSD17B11 LRRC4C MTIF3 MYO7A PGRMC2 RMDN2 SACM1L TLCD4 TMEM201 TSNARE1	12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN
Entrez ID		55591	4647
HPRD ID		11671	02043
Ensembl ID		ENSG00000028203	ENSG00000137474
Uniprot IDs		Q9HBM0	Q13402
PDB IDs			5MV9
Enriched GO Terms of Interacting Partners?
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