MYO7A and MAP2

Data Source:
HPRD (in vivo)

		MYO7A	MAP2
Description		myosin VIIA	microtubule associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Dendrite Dendrite Cytoplasm Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Axon Hillock Dendritic Growth Cone Main Axon Dendritic Branch Basal Dendrite Primary Dendrite Distal Dendrite Apical Distal Dendrite Dendritic Filopodium Proximal Dendrite Proximal Neuron Projection
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding Tau Protein Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Dendrite Development Central Nervous System Neuron Development Negative Regulation Of Axon Extension Regulation Of Microtubule Polymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Dendrite Morphogenesis Positive Regulation Of Anterograde Dense Core Granule Transport Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Anterograde Synaptic Vesicle Transport Regulation Of Cellular Protein Localization Negative Regulation Of Microtubule Binding Negative Regulation Of Microtubule Motor Activity
Pathways		The canonical retinoid cycle in rods (twilight vision)
Drugs			Estramustine Paclitaxel Docetaxel
Diseases		Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)	Adventurousness ( 30643258) Bipolar disorder ( 31043756) Body mass index ( 28552196) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Handedness (Left-handed vs. non-left-handed) ( 31504236 30980028) Handedness (left-handed vs. right-handed) ( 31504236) Height ( 28552196) Left-handedness ( 32989287) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN	25 interacting genes: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MDM2 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A
Entrez ID		4647	4133
HPRD ID		02043	01140
Ensembl ID		ENSG00000137474	ENSG00000078018
Uniprot IDs		Q13402	A0A024R3Y8 A0A024R3Z1 A0A024R409 P11137 Q6NYC5
PDB IDs		5MV9
Enriched GO Terms of Interacting Partners?
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