MYO7A and VEZT

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MYO7A	VEZT
Description		myosin VIIA	vezatin, adherens junctions transmembrane protein
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density	Acrosomal Vesicle Stereocilia Ankle Link Complex Nucleoplasm Cytosol Adherens Junction Integral Component Of Membrane Stereocilium Membrane
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding	Myosin Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization	Cell-cell Adhesion
Pathways		The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)	Brain morphology (MOSTest) ( 32665545) Endometriosis ( 23104006 23472165 28537267) Pursuit maintenance gain ( 29064472)
Interacting Genes		12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN	16 interacting genes: ANKS6 AQP6 C5 CMTM3 CREB3L1 GORAB HSD17B11 LRRC4C MTIF3 MYO7A PGRMC2 RMDN2 SACM1L TLCD4 TMEM201 TSNARE1
Entrez ID		4647	55591
HPRD ID		02043	11671
Ensembl ID		ENSG00000137474	ENSG00000028203
Uniprot IDs		Q13402	Q9HBM0
PDB IDs		5MV9
Enriched GO Terms of Interacting Partners?
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