RMDN3 and PELI2

Data Source:
BioGRID (two hybrid)

		RMDN3	PELI2
Description		regulator of microtubule dynamics 3	pellino E3 ubiquitin protein ligase family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Spindle Microtubule Integral Component Of Membrane Organelle Membrane Contact Site Intercellular Bridge Mitotic Spindle Pole	Cytosol
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Cellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Toll Signaling Pathway Regulation Of Toll Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Interleukin-1-mediated Signaling Pathway
Pathways			Interleukin-1 signaling IRAK1 recruits IKK complex IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061) Refractive error ( 32231278)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Body mass index (smoking years interaction) ( 23192594) Body mass index (ever vs never smoking interaction) ( 23192594) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) End-stage kidney disease ( 31178898) Height ( 25133637) Nickel levels ( 26025379) Telomere length ( 21460395)
Interacting Genes		25 interacting genes: CYB561D2 EGFL8 EMP3 FAM3C GIMAP1 LHFPL5 NRM PELI2 PLP1 PSEN1 SLC13A3 SLC30A8 STX2 STX3 TF TFRC TMEM100 TMEM140 TMEM147 TMEM203 TMEM243 VAMP3 VKORC1 YWHAB YWHAG	34 interacting genes: BCL10 CLEC17A CREB3L3 DEAF1 ERO1A FN1 FRYL HNRNPK HYAL2 IRAK1 IRAK2 IRAK4 LAMC3 LTBP3 LZTFL1 MDFI MEOX1 MYD88 NUP62 OR7D2 PCGF2 PICALM RABEP1 REL RMDN3 SEPTIN3 SP4 SRPK1 THAP7 TMEM79 TP53 TP63 TRIM32 UBQLN4
Entrez ID		55177	57161
HPRD ID		07687	17835
Ensembl ID		ENSG00000137824	ENSG00000139946
Uniprot IDs		A0A024R9P6 Q96TC7	Q9H716 Q9HAT8
PDB IDs			3EGA 3EGB
Enriched GO Terms of Interacting Partners?
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