TESC and RAI1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TESC	RAI1
Description		tescalcin	retinoic acid induced 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Ruffle Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Population Proliferation Male Gonad Development Positive Regulation Of Gene Expression Protein Transport Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Localization To Plasma Membrane	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription, DNA-templated
Pathways			Circadian Clock
Drugs
Diseases			Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
GWAS		Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Total hippocampal volume ( 30279459)	Body mass index ( 28892062) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Hip circumference ( 25673412) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 27863252) Offspring birth weight ( 31043758) Parkinson's disease ( 21738487) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458 30297969)
Interacting Genes		6 interacting genes: CCDC91 DYNLT3 HMG20A RAI1 SLC9A1 WBP11	17 interacting genes: CASP2 CDKN1A DDIT3 GADD45A GATA1 GLI1 GSK3B LZTR1 MAML3 MAPK8IP2 PIN1 RPS6KA5 TESC TET2 TOPBP1 TTR ZNF496
Entrez ID		54997	10743
HPRD ID		11649	07406
Ensembl ID		ENSG00000088992	ENSG00000108557
Uniprot IDs		Q96BS2	Q7Z5J4
PDB IDs
Enriched GO Terms of Interacting Partners?
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