RAI1 and TESC

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAI1	TESC
Description		retinoic acid induced 1	tescalcin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Ruffle Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Population Proliferation Male Gonad Development Positive Regulation Of Gene Expression Protein Transport Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Localization To Plasma Membrane
Pathways		Circadian Clock
Drugs
Diseases		Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
GWAS		Body mass index ( 28892062) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Hip circumference ( 25673412) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 27863252) Offspring birth weight ( 31043758) Parkinson's disease ( 21738487) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458 30297969)	Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Total hippocampal volume ( 30279459)
Interacting Genes		17 interacting genes: CASP2 CDKN1A DDIT3 GADD45A GATA1 GLI1 GSK3B LZTR1 MAML3 MAPK8IP2 PIN1 RPS6KA5 TESC TET2 TOPBP1 TTR ZNF496	6 interacting genes: CCDC91 DYNLT3 HMG20A RAI1 SLC9A1 WBP11
Entrez ID		10743	54997
HPRD ID		07406	11649
Ensembl ID		ENSG00000108557	ENSG00000088992
Uniprot IDs		Q7Z5J4	Q96BS2
PDB IDs
Enriched GO Terms of Interacting Partners?
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