RAI1 and ZNF496

Data Source:
BioGRID (two hybrid)

		RAI1	ZNF496
Description		retinoic acid induced 1	zinc finger protein 496
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus
	Molecular Function	Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated
Pathways		Circadian Clock	Generic Transcription Pathway
Drugs
Diseases		Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
GWAS		Body mass index ( 28892062) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Hip circumference ( 25673412) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 27863252) Offspring birth weight ( 31043758) Parkinson's disease ( 21738487) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458 30297969)	Chromium levels ( 26025379) Platelet distribution width ( 32888494)
Interacting Genes		17 interacting genes: CASP2 CDKN1A DDIT3 GADD45A GATA1 GLI1 GSK3B LZTR1 MAML3 MAPK8IP2 PIN1 RPS6KA5 TESC TET2 TOPBP1 TTR ZNF496	23 interacting genes: ARR3 CBX3 JADE2 NR3C1 NSD1 PGBD1 POLR3D PPARG RAI1 RNF8 SCAND1 SSX3 SUMO2 SUMO3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZNF483 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3
Entrez ID		10743	84838
HPRD ID		07406	15805
Ensembl ID		ENSG00000108557	ENSG00000162714
Uniprot IDs		Q7Z5J4	Q96IT1
PDB IDs
Enriched GO Terms of Interacting Partners?
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