PGM1 and DNAJB6

Data Source:
BioGRID (two hybrid)

		PGM1	DNAJB6
Description		phosphoglucomutase 1	DnaJ heat shock protein family (Hsp40) member B6
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Galactose Catabolic Process Neutrophil Degranulation	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		Glycogen synthesis Defective PGM1 causes PGM1-CDG (CDG1t) Neutrophil degranulation	Regulation of HSF1-mediated heat shock response
Drugs		Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate
Diseases
GWAS		Alcohol consumption (transferrin glycosylation) ( 21665994) Blood protein levels ( 29875488) Type 1 diabetes ( 32005708 19430480) Type 2 diabetes ( 32499647)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		16 interacting genes: APP DNAJB6 ENO3 HSPB2 KIF1B LINC01554 NLRP3 PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		5236	10049
HPRD ID		01389	07107
Ensembl ID		ENSG00000079739	ENSG00000105993
Uniprot IDs		B4DDQ8 B7Z6C2 P36871	A0A0J9YX62 O75190
PDB IDs		5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6SNO 6SNP 6SNQ 6UIQ 6UO6	6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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