PGM1 and S100A1

Data Source:
HPRD (in vitro)

		PGM1	S100A1
Description		phosphoglucomutase 1	S100 calcium binding protein A1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Extracellular Region Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Sarcoplasmic Reticulum Protein-containing Complex
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Galactose Catabolic Process Neutrophil Degranulation	Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Sprouting Angiogenesis
Pathways		Glycogen synthesis Defective PGM1 causes PGM1-CDG (CDG1t) Neutrophil degranulation	Regulation of TLR by endogenous ligand
Drugs		Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate	Olopatadine
Diseases
GWAS		Alcohol consumption (transferrin glycosylation) ( 21665994) Blood protein levels ( 29875488) Type 1 diabetes ( 32005708 19430480) Type 2 diabetes ( 32499647)
Interacting Genes		16 interacting genes: APP DNAJB6 ENO3 HSPB2 KIF1B LINC01554 NLRP3 PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4	30 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BEX3 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A3 S100A4 S100B S100P S100Z SYN1
Entrez ID		5236	6271
HPRD ID		01389	01489
Ensembl ID		ENSG00000079739	ENSG00000160678
Uniprot IDs		B4DDQ8 B7Z6C2 P36871	A0A0S2Z4H2 P23297
PDB IDs		5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6SNO 6SNP 6SNQ 6UIQ 6UO6	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?