PGM1 and KIF1B

Data Source:
BioGRID (two hybrid)

		PGM1	KIF1B
Description		phosphoglucomutase 1	kinesin family member 1B
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding
	Biological Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Galactose Catabolic Process Neutrophil Degranulation	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery
Pathways		Glycogen synthesis Defective PGM1 causes PGM1-CDG (CDG1t) Neutrophil degranulation	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs		Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Alcohol consumption (transferrin glycosylation) ( 21665994) Blood protein levels ( 29875488) Type 1 diabetes ( 32005708 19430480) Type 2 diabetes ( 32499647)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)
Interacting Genes		16 interacting genes: APP DNAJB6 ENO3 HSPB2 KIF1B LINC01554 NLRP3 PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4	22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG
Entrez ID		5236	23095
HPRD ID		01389	05818
Ensembl ID		ENSG00000079739	ENSG00000054523
Uniprot IDs		B4DDQ8 B7Z6C2 P36871	O60333
PDB IDs		5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6SNO 6SNP 6SNQ 6UIQ 6UO6	2EH0
Enriched GO Terms of Interacting Partners?
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